Full employer posting
The Pereira Laboratory at the Icahn School of Medicine investigates the neurobiology of Alzheimer's disease, including the selective regional and cellular vulnerability to tau pathology and neurodegeneration. We are seeking an outstanding Associate Scientist to join the lab's efforts to discover and validate novel therapeutic targets using animal models, postmortem human tissue, iPSCs, and bioinformatics. Responsibilities Perform in vivo experiments using mouse models, including stereotaxic injections.
Conduct molecular and cell biology experiments to support ongoing research projects. Perform laboratory techniques, including cell culture, DNA/RNA isolation, cellular fractionation, Western blotting, PCR/qRT-PCR, in situ hybridization, and immunohistochemical labeling. Conduct research to develop methodologies, instrumentation, and procedures for medical applications, including analyzing data and presenting findings.
Design and conduct complex research studies, evaluating alternative methods, computational models, and experimental approaches. Plan and conduct studies investigating human or animal diseases, preventive methods, and potential treatments. Assist in clinical laboratory operations, as needed.
Follow established laboratory safety procedures to prevent contamination and ensure compliance with safety standards. Provide training and guidance on medical and laboratory procedures to physicians, residents, students, and research staff. Collaborate with healthcare professionals, researchers, and other stakeholders to support research initiatives and health safety standards.
Develop research tools, techniques, and methodologies to support scientific investigations. Identify research questions, develop hypotheses, and establish methodologies for evaluating experimental results. Analyze and interpret research findings and communicate results through scientific publications and presentations.
Develop research proposals and seek support for new and ongoing research activities. Provide scientific recommendations to support research activities and project objectives. Perform other related duties.
Qualifications Ph. D. in Biological Science or related field Three years' experience Highly Preferred
Extensive experience working with mouse models, including performing stereotaxic injections. Strong background in molecular and cell biology. Experience with laboratory techniques, including cell culture, DNA/RNA isolation, cellular fractionation, Western blotting, PCR/qRT-PCR, in situ hybridization, and immunohistochemical labeling.
Strong interest in neurodegeneration highly preferred. Demonstrated self-motivation, enthusiasm, and scientific rigor. Ability to work independently at the bench.
Full time · Day shift
About the role
The Pereira Laboratory at the Icahn School of Medicine investigates the neurobiology of Alzheimer's disease, including the selective regional and cellular vulnerability to tau pathology and neurodegeneration. We are seeking an outstanding Associate Scientist to join the lab's efforts to discover and validate novel therapeutic targets using animal models, postmortem human tissue, iPSCs, and bioinformatics.